TERMINALIA CHEBULA: SUCCESS FROM BOTANY TO ALLOPATHIC AND AYURVEDIC PHARMACY

Authors

  • Varun Garg School of Pharmaceutical Sciences, Lovely Professional University, Punjab, India
  • Barinder Kaur School of Pharmaceutical Sciences, Lovely Professional University, Punjab, India
  • Sachin Kumar Singh School of Pharmaceutical Sciences, Lovely Professional University, Punjab, India
  • Bimlesh Kumar School of Pharmaceutical Sciences, Lovely Professional University, Punjab, India

DOI:

https://doi.org/10.22159/ajpcr.2016.v9i5.13074

Abstract

Terminalia chebula (TC) is a unique herb having various therapeutic potentials as anti-inflammatory, antioxidant, anticancer, and digestant. It belongs to family Combretaceae. In the present review, an attempt has been made to decipher classification, chemical constituents, therapeutic uses, and patents that have been reported for TC. Various pharmacological activities of TC that make it as potential medicine and its Ayurvedic formulations are highlighted.

Keywords: Terminalia chebula, Anti-oxidant, Anti-cancer, Ayurvedic formulations, Anti-oxidant.

Downloads

Download data is not yet available.

References

Bag A, Kumar Bhattacharyya S, Kumar Pal N, Ranjan Chattopadhyay R. Anti-inflammatory, anti- lipid peroxidative, antioxidant and membrane stabilizing activity of hydroalcoholic extract of Terminalia chebula fruits.Pharm Biol 2013;5(12):1515-20.

Jami SI, Sultana Z, Ali E, Begum M, Haque M. Evaluation of analgesic and anti – Inflammatory activities on ethanolic extract of Terminalia chebula fruits in experimental animal models. AJIPS 2014;5(1):63-9.

Han Q, Song J, Qiao C, Wong L, Xu H. Preparative isolation of hydrolysable tannins chebulagic acid and chebulinic acid from Terminalia chebula by high-speed counter-current chromatography. J Sep Sci 2006;29(11):1653-7.

Mahajan A, Pai N. Simultaneous isolation and identification of phytoconstituents from Terminalia chebula by preparative chromatography. J Chem Pharm Res 2010;2(5):97-103.

Pfundstein B, El Desouky SK, Hull WE, Haubner R, Erben G, Owen RW. Polyphenolic compounds in the fruits of Egyptian medicinal plants (Terminalia bellerica, Terminalia chebula and Terminalia horrida): Characterization, quantitation and determination of antioxidant capacities. Phytochemistry 2010;71(10):1132-485.

Sastry JL. Dravyaguna Vijnana. Vol. 2. Reprint 2008. Varanasi: Chaukhambha Orientalia; 2008. p. 210.

Gogte UV. Ayurvedic Pharmacology and Therapeutic uses of Medicinal Plants. Reprint 2009. New Delhi: Chaukhamba Orientalia; 2009. p. 515-9.

Nadkarni AK. Indian Materia Medica. Reprint 2010. Mumbai: Popular Prakashan; 2010. p. 2016.

Hooker JD. Flora of British India. Part-2. London: Oxford; 1854. p. 443-9.

Ratha KK, Joshi GC. Haritaki (Chebulic myrobalan) and its varieties. Ayu 2013;34(3):331-4.

Chunekar KC. Bhavaprakash Nighantu. Varanasi: Chaukhamba Bharati Academy; 1999. p. 4-5.

Sharma PV, Sharma GP. Nighantu of Kaiyadeva. 1st ed. Varanasi: Chaukhamba Orientalia, Kaiyadevnighantu; 1979. p. 45.

Vaidya B. Nighantu Adarsa. 1st ed. Varanasi: Chaukhambha Vidya Bhavan; 1968. p. 551-4.

Klika KD, Saleem A, Sinkkonen J, Kähkönen M, Loponen J, Tähtinen P, et al. The structural and conformational analyses and antioxidant activities of chebulinic acid and its thrice-hydrolyzed derivative, 2,4-chebuloyl-β-D-glucopyranoside, isolated from the fruit of Terminalia chebula. ARKIVOC 2004;7:83-105.

Mahajan AD, Pai NR. Development and validation of HPLC method for quantification of phytoconstituents in Haritaki churna. Int J Chem Tech Res 2011;3(1):329-36.

Tannins. Available from: http://www.pharmaxchange.info/press/?s=tannins. [Last cited on 2014 Aug 12].

Sahrma PC, Yelne MB, Dennis TJ, Joshi A. Database on Medicinal Plants in Ayurveda. Vol. 2. Reprint 2005. New Delhi: Documentation and Publication Division, CCRAS; 2005. p. 29.

Sabina EP, Rasool M. An in vivo and in vitro potential of Indian Ayurvedic herbal formulation Triphala on experimental gouty arthritis in mice. Vascul Pharmacol 2008;48(1):14-20.

Reddy DB, Reddy TC, Jyotsna G, Sharan S, Priya N, Lakshmipathi V, et al. Chebulagic acid, a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz. Induces apoptosis in COLO-205 cell line. J Ethnopharmacol 2009;124(3):506-12.

Oyuntsetseg N, Khasnatinov MA, Molor-Erdene P, Oyunbileg J, Liapunov AV, Danchinova GA, et al. Evaluation of direct antiviral activity of the Deva-5 herb formulation and extracts of five Asian plants against influenza A virus H3N8. BMC Complement Altern Med 2014;14:235.

Ma H, Diao Y, Zhao D, Li K, Kang T. A new alternative to treat swine influenza A virus infection: Extracts from Terminalia chebula Retz. Afr J Microbiol Res 2010;4(6):497-9.

Saleem A, Husheem M, Härkönen P, Pihlaja K. Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula Retz. Fruit. J Ethnopharmacol 2002;81(3):327-36.

Yi ZC, Liu YZ, Li HX, Yin Y, Zhuang FY, Fan YB, et al. Tellimagrandin I enhances gap junctional communication and attenuates the tumor phenotype of human cervical carcinoma Hela cells in vitro. Cancer Lett 2006;242(1):77-87.

Kaur S, Grover IS, Singh M, Kaur S. Antimutagenicity of hydrolyzable tannins from Terminalia chebula in Salmonella typhimurium. Mutat Res 1998;419(1-3):169-79.

Prasad L, Husain Khan T, Jahangir T, Sultana S. Chemomodulatory effects of Terminalia chebula against nickel chloride induced oxidative stress and tumor promotion response in male Wistar rats. J Trace Elem Med Biol 2006;20(4):233-9.

Sharma P, Prakash T, Kotresha D, Ansari MA, Sahrm UR, Kumar B, et al. Antiulcerogenic activity of Terminalia chebula fruit in experimentally induced ulcer in rats. Pharm Biol 2011;49(3):262-8.

Lee H, Lee JY, Suh MH, Sim SS, Lee MW, Kim CJ. Hydrolysable tannins depress cardiac papillary muscle contraction and propranolol-induced negative inotropism. Fitoterapia 2010;81(7):820-5.

Guan YY, Kwan CY, Hsu FL, Cheng JT. In vitro inhibitory effects of chebulinic acid on the contractile responses of cardiovascular muscles. Clin Exp Pharmacol Physiol 1996;23(8):747-50.

Suchalatha S, Srinivasan P, Devi CS. Effect of T. chebula on mitochondrial alterations in experimental myocardial injury. Chem Biol Interact 2007;169(3):145-53.

Thakur CP, Thakur B, Singh S, Sinha PK, Sinha SK. The Ayurvedic medicines Haritaki, Amala and Bahira reduce cholesterol-induced atherosclerosis in rabbits. Int J Cardiol 1988;21(2):167-75.

Lee HS, Koo YC, Suh HJ, Kim KY, Lee KW. Preventive effects of chebulic acid isolated from Terminalia chebula on advanced glycation endproduct-induced endothelial cell dysfunction. J Ethnopharmacol 2010;131:567-74.

Sasidharan I, Sundaresan A, Nisha VM, Kirishna MS, Raghu KG, Jayamurthy P. Inhibitory effect of Terminalia chebula Retz. Fruit extracts on digestive enzyme related to diabetes and oxidative stress. J Enzyme Inhib Med Chem 2012;27(4):578-86.

Gupta A, Mishra AK, Bansal P, Singh R, Kumar S, Gupta V. Phytochemistry and pharmacological activities of Haritaki - A review. J Pharm Res 2010;3(2):417.

Gandhi NM, Nair CK. Radiation protection by Terminalia chebula: Some mechanistic aspects. Mol Cell Biochem 2005;277(1-2):43-8.

Jagetia GC, Baliga MS, Malagi KJ, Sethukumar Kamath M. The evaluation of the radioprotective effect of Triphala (An Ayurvedic rejuvenating drug) in the mice exposed to gamma-radiation. Phytomedicine 2002;9(2):99-108.

Weaver JL, Pine PS, Dutschman G, Cheng YC, Lee KH, Aszalos A. Prevention of binding of rgp120 by anti-HIV active tannins. Biochem Pharmacol 1992;43(11):2479-80.

Nakashima H, Murakami T, Yamamoto N, Sakagami H, Tanuma S, Hatano T, et al. Inhibition of human immunodeficiency viral replication by tannins and related compounds. Antiviral Res 1992;18(1):91-103.

Naik GH, Priyadarsini KI, Satav JG, Banavalikar MM, Sohoni DP, Biyani MK, et al. Comparative antioxidant activity of individual herbal components used in Ayurvedic medicine. Phytochemistry 2003;63(1):97-104.

Surveswaran S, Cai YZ, Corke H, Sun M. Systematic evaluation of natural phenolic antioxidants from 133 Indian medicinal plants. Food Chem 2007; 102:938-53.

Yokozawa T, Chen CP, Dong E, Tanaka T, Nonaka GI, Nishioka I. Study on the inhibitory effect of tannins and flavonoids against the 1,1-diphenyl-2 picrylhydrazyl radical. Biochem Pharmacol 1998;56(2):213-22.

Okuda T. Systematics and health effects of chemically distinct tannins in medicinal plants. Phytochemistry 2005;66(17):2012-31.

Hikino H, Kiso Y, Hatano T, Yoshida T, Okuda T. Antihepatotoxic actions of tannins. J Ethnopharmacol 1985;14(1):19-29.

Kalidindi SR. Use of Terminalia chebula extract for treatment of osteoarthritis. US Patent 20150174184. 2014. Available from: https://www.patentscope.wipo.int/search/en/result.jsf? currentNavigationRow=next&prevCurrentNavigationRow =1&query=Terminalia%20chebula&office= &sortOption= Pub%20Date%20Desc&prevFilter=&maxRec=579. [Last cited on 2015 Oct 12].

Gokila T, Rajalekshmi M, Haridasan C, Eleke S, Hilde W, Ilse M. Plants parts and extracts having anticoccidal activity. EP Patent 2866794. 2015. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf? docId= EP133271519&recNum = 21&office= &queryString= Terminalia+chebula&prevFilter= &sortOption= Pub+Date+Desc&maxRec= 579. [Last cited on 2015 Oct 12].

Kalidindi SR. Terminalia chebula and Terminalia bellerica extracts for inhibition of xanthine oxidase.US Patent 20150050369. 2015. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= US130579967&redirectedID= true. [Last cited on 2015 Oct 12].

Rihua H. Weight-reducing tea and preparation method thereof. CN Patent 103976056. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN107124602&redirectedID= true. [Last cited on 2015 Oct 12].

Wuxian Z, Qunxing L, Yingting Z. Traditional Chinese medicine preparation for effectively treating dry cough. CN Patent 103933435. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN106893674&redirectedID= true. [Last cited on 2015 Oct 12].

Jianhua C, Xiaoqun L, Yifeng L, Xiaoxia W. Tea with function of smoking cessation. CN Patent 103892005. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN105753730&redirectedID= true. [Last cited on 2015 Oct 12].

Yongda Z, Fengying M, Haining F. Broad-spectrum anti-toxic and bacteriostatic traditional Chinese medicine preparation and preparation method there of. CN Patent 103877320. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN105724061&redirectedID= true. [Last cited on 2015 Oct 12].

Hongxia Y. Concentrated solution capable of clearing heat and removing toxicity. CN Patent 103860859. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN105527443&redirectedID= true. [Last cited on 2015 Oct 12].

Gokila T, Rajalekshmi M, Haridasan C, Hannah K. Plant parts and extracts having anticoccidial activity. US Patent 20140161919. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= US97881695&redirectedID= true. [Last cited on 2015 Oct 12].

Kuerban S, Saidula A, Lixiny I, Ping W, Ainiwaer R, Yasen W, et al. Blood purifying mixture for treating skin diseases. CN Patent 103830379. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN105274255&redirectedID= true. [Last cited on 2015 Oct 12].

Fengqin Y, Shengjie W. Physalisalkekengi heat-clearing throat-wetting wine and production method thereof. CN Patent 103815400. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN97697098&redirectedID= true. [Last cited on 2015 Oct 12].

Tongwei A, Qingzhong C, Jia G. Compound tincture for treatment of porcine virus diarrhea, preparation method and application thereof. CN Patent 103800804. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN97673714&redirectedID= true. [Last cited on 2015 Oct 12].

Fengqin Y, Shengjie W. Blueberry wine with functions of invigorating stomach and relieving diarrhea and production method thereof. CN Patent 103805422. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN97685595&redirectedID= true. [Last cited on 2015 Oct 12].

Qun Z. Traditional Chinese medicine effective part composition for treating chronic pharyngitis. CN Patent 103768138. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN97456815&redirectedID= true. [Last cited on 2015 Oct 12].

Wenge Z, Chuansheng L, Yanli M, Ting S. Traditional Chinese medicinal decoction for treating bronchial asthma. CN Patent 103751674. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN97444765&redirectedID= true. [Last cited on 2015 Oct 12].

Linxiang W, Yuwen W, Shaoqin C. Drug for treatment of rheumatoid arthritis and preparation method thereof. CN Patent 10375130. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN97436452&redirectedID= true. [Last cited on 2015 Oct 12].

Banglin S. Traditional Chinese medicine preparation for treating tonsillitis and pharyngolaryngitis and preparation method thereof. CN Patent 103690695. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN97363310&redirectedID= true. [Last cited on 2015 Oct 12].

Zhaoshun H, Xiaoying C, Xue H, Bing H. Chinese herbal medicine feed for wide geese, wide ducks, African geese and wide chickens. CN Patent 103621837. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN96911073&redirectedID= true. [Last cited on 2015 Oct 12].

Zhen W. Traditional Chinese medicine (TCM) for treating allergic rhinitis. CN Patent 103610788. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN96890928&redirectedID= true. [Last cited on 2015 Oct 12].

Hong Z. Throat clearing and moistening healthcare tea. CN Patent 103493921. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN97998265&redirectedID= true. [Last cited on 2015 Oct 12].

Thangavel G, Mukklil R, Chirakkal H, Kurian H, Schoeters E, Wouters H, et al. Plant parts and extracts having anticoccidial activity. WO Patent 2014004761. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= WO2014004761&redirectedID= true. [Last cited on 2015 Oct 12].

Qing L. External powder for treating dental ulcer and preparation method thereof. CN Patent 103405578. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN97906141&redirectedID= true. [Last cited on 2015 Oct 12].

Ghosal S, Veeraragavan M, Kalidindi SR. Terminalia chebula compositions and method of extracting same. WO Patent 2013155175. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= WO2013155175&redirectedID= true. [Last cited on 2015 Oct 12].

Lee KW, Lee JY, Hong CO, Koo YC, Nam MH, Yang SY. Inhibitor and a breaker of an advance glycation end-products (AGEs) - induced crosslink, containing chebulic acid as an active ingredient. Kr Patent 1020130109874. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= kr95738165&recNum= 2&office= &queryString= FP%3A%281020130109874%29&prevFilter= &sortOption= Pub+Date+Desc&maxRec= 2. [Last cited on 2015 Oct 12].

Divya R, Kumar RR, Kunnambath R, Radhakrishna PM. Mouthwash composition for managing oral mucositis, process and methods thereof. US Patent 20130243702. 2014. Available from:

https://www.patentscope.wipo.int/search/en/detail.jsf?docId= US91083848&redirectedID= true. [Last cited on 2015 Oct 12].

Liugui W, Jianying L. Quality control method of drug for treating cough. CN Patent 103175938. 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN91950202&redirectedID= true. [Last cited on 2015 Oct 12].

Kim, Choi HB, Lim HT, Kim HJ, Lee JS, Bae JY, et al. Cosmetic composition containing Indian natural products for skin whitening. Kr Patent 1020130057542, 2014. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= kr95439272&redirectedID= true. [Last cited on 2015 Oct 12].

Hongqi ZA. Chinese medicinal formulation for treating infiltrative pulmonary tuberculosis. CN Patent 102847026. 2013. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN85772836&redirectedID= true. [Last cited on 2015 Oct 12].

Hongqi ZA. Chinese medicinal formulation for treating tuberculosis of intestine. CN Patent 102847027. 2013Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN85772881&redirectedID= true. [Last cited on 2015 Oct 12].

Yang X, Qiongguang Z, Fuliang X. Traditional Chinese medicine for treating fungal skin infection. CN Patent 102824518. 2013. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN85444998&redirectedID= true. [Last cited on 2015 Oct 12].

Pengcuo J. Traditional Tibetan medicine for treating alopecia. CN Patent 102784216. 2013. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= true CN85410828&redirectedID= . [Last cited on 2015 Oct 12].

Junjie X. Traditional Chinese medicine preparation for treating viral enteritis and diarrhea. CN Patent 102670936. 2013. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN85312413&redirectedID= true. [Last cited on 2015 Oct 12].

Unilever Herb extract for cognitive health benefit. EP Patent 2486932. 2012. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= EP73124109&recNum= 2&office= &queryString= FP%3A%282486932%29&prevFilter= &sortOption= Pub+Date+Desc&maxRec= 6. [Last cited on 2015 Oct 12].

Changtao W, Xiaotao S, Xingding C, Shuang W. Antioxidant active compound of Terminalia chebula and preparation method thereof. CN Patent 102526136. 2012. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN85165872&redirectedID= true. [Last cited on 2015 Oct 12].

Eileen KP, Awerkwei QR. Hair treatment composition. EP Patent 2467191. 2012. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= EP57543417&recNum= 3&office= &queryString= FP%3A%282467191%29&prevFilter= &sortOption= Pub+Date+Desc&maxRec= 6. [Last cited on 2015 Oct 12].

Eileen KP. Hair treatment composition. US Patent 20120138079. 2012. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= US73585302&redirectedID= true. [Last cited on 2015 Oct 12].

Divya R, Kumar RK, Ramadas R, Pillai K, Radhakrishna M. A mouthwash composition for managing oral mucositis, process and methods thereof. WO Patent 2012059874. 2012. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= WO2012059874&redirectedID= true. [Last cited on 2015 Oct 12].

Namita D. Plant extracts, compositions containing same, and uses thereof. US Patent 20120027697. 2012. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= US73474925&redirectedID= true. [Last cited on 2015 Oct 12].

Hui L. Chinese composition for treating rhinitis. CN Patent 102284035. 2011. Available from: https://www.psatentscope.wipo.int/search/en/detail.jsf?docId= CN84865093&redirectedID= true. [Last cited on 2015 Oct 12].

Han SL. Pharmaceutical composition containing Terminalia chebula Retzius extarct for or treating dermatitis. Kr Patent 1020110108825. 2011. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= kr45543869&recNum= 2&office= &queryString= FP%3A%281020110108825%29&prevFilter= &sortOption= Pub+Date+Desc&maxRec= 2. [Last cited on 2015 Oct 12].

Morawala PV. Screening method (metabolite grid) for therapeutic extracts and molecules for diabetes. US Patent 20110159118. 2011. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= US73285153&redirectedID= true. [Last cited on 2015 Oct 12].

Chai NY, Jung YG, Kim KH, Choi KS, Sun K. NF-kappa B inhibitor containing Terminalia chebula fruit extarct. Kr Patent 1020110073241. 2011. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= kr45510446&recNum= 2&office= &queryString= FP%3A%281020110073241%29&prevFilter= &sortOption= Pub+Date+Desc&maxRec= 2. [Last cited on 2015 Oct 12].

Zhiying C, Linsheng L, Xiaohong Y, Chunling C, Dexiu W, Dexiu Q. Compound Terminalia chebula Retz throat lozenge and preparation method thereof. CN Patent 102100326. 2011. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= CN84676334&redirectedID= true. [Last cited on 2015 Oct 12].

Yoon HG, Kim HG, Lee MI, Jun YH, Jin W. Method for preparing Terminalia chebula extract for preventing or treating prostate cancer. Kr Patent 1020110048133. 2011. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= kr30062298&recNum= 2&office= &queryString= FP%3A%281020110048133%29&prevFilter= &sortOption= Pub+Date+Desc&maxRec= 2. [Last cited ON 2015 Oct 12].

Penelope K, Quartey E, Awerkwei R. Hair treatment composition. WO Patent 2011020833. 2010. Available from: https://www.patentscope.wipo.int/search/en/detail.jsf?docId= WO2011020833&redirectedID= true. [Last cited on 2015 Oct 12].

Yi ZC, Wang Z, Li HX, Liu MJ, Wu RC, Wang XH. Effects of chebulinic acid on differentiation of human leukemia K562 cells. Acta Pharmacol Sin 2004;25(2):231-8.

Published

01-09-2016

How to Cite

Garg, V., B. Kaur, S. K. Singh, and B. Kumar. “TERMINALIA CHEBULA: SUCCESS FROM BOTANY TO ALLOPATHIC AND AYURVEDIC PHARMACY”. Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 5, Sept. 2016, pp. 21-28, doi:10.22159/ajpcr.2016.v9i5.13074.

Issue

Section

Review Article(s)

Most read articles by the same author(s)

1 2 > >>