GREEN TEA EXTRACT IN AN EYELASH GROWTH ENHANCER GEL FORMULATION: STABILITY TEST, EYE IRRITATION TEST, AND HUMAN EYELASH GROWTH ACTIVITY

Authors

  • Indra Syahputra Roes Lie Department of Cosmetology, Faculty of Pharmacy, University of Indonesia, Kampus UI Depok, 16424, West Java Indonesia.
  • Joshita Djajadisastra Department of Cosmetology, Faculty of Pharmacy, University of Indonesia, Kampus UI Depok, 16424, West Java Indonesia.
  • Fadlina Chany Saputri Department of Cosmetology, Faculty of Pharmacy, University of Indonesia, Kampus UI Depok, 16424, West Java Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i6.18605

Keywords:

Green tea extract, Eyelash gel, Stability test, Nil, Eyelash growth activity

Abstract

Objective: To formulate a green tea extract (GTE), which is often used as a hair growth product, to produce an eyelash gel with good stability, effectiveness, and safety for growing eyelashes.

Methods: GTE was formulated into a gel. A stability test was performed at a high temperature (40±2°C), room temperature (25±2°C), low temperature (4±2°C), and a cycling temperature. An in vitro hen's egg test-chorioallantoic membrane assay was performed to evaluate potential eye irritation. An eyelash growth test was conducted by length measurement using an eyelash ruler before and after 2 mo of application in human volunteers.

Results: The GTE gel was stable in storage at high, room, and low temperatures and at cycling temperatures and did not cause eye irritation. Eyelashes grew significantly more in the test group than in the placebo group after 2 mo of application (p<0.05).

Conclusion: GTE gel provides a new, safe, and effective option for growing natural eyelashes.

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Published

2017-06-01

How to Cite

Roes Lie, I. S., J. Djajadisastra, and F. C. Saputri. “GREEN TEA EXTRACT IN AN EYELASH GROWTH ENHANCER GEL FORMULATION: STABILITY TEST, EYE IRRITATION TEST, AND HUMAN EYELASH GROWTH ACTIVITY”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 6, June 2017, pp. 243-6, doi:10.22159/ajpcr.2017.v10i6.18605.

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