AN INTRIGUING CAUSE OF CHRONIC DIARRHEA – PROTEIN-LOSING ENTEROPATHY AS THE PRESENTING MANIFESTATION OF SYSTEMIC LUPUS ERYTHEMATOSUS

Authors

  • Satish H Department of Gastroenterology, Apollo Hospital, Chennai, Tamil Nadu, India.
  • Hariharan M Department of Gastroenterology, Apollo Hospital, Chennai, Tamil Nadu, India.
  • Navin Patil Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Udupi, Karnataka, India.
  • Karthik Rao Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Udupi, Karnataka, India
  • Balaji Ommurugan Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Udupi, Karnataka, India
  • Satish Nayak B Department of Gastroenterology, Kasturba Medical College, Manipal University, Manipal, Udupi, Karnataka, India.

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i7.18880

Keywords:

Systemic lupus, Protein losing enteropathy, Diarrhea, Bowel wall edema

Abstract

ABSTRACT

Systemic lupus erythematosus (SLE) is a systemic autoimmune inflammatory disease.  It presents with myriad of clinical manifestations affecting every other organ system in human body. The gastrointestinal system is one of the commonest affected and it involves any part of the GI tract with incidences ranging from 1.3% to 27.5%. Gastrointestinal manifestations as a presenting feature of SLE is unusual. Chronic diarrhea due to protein losing enteropathy as the presenting manifestation of SLE is very rare and a diagnosis of SLE should be kept in mind when other systemic manifestations are absent. Hence, we report a 29-year-old female with chronic diarrhea as the main manifestation of SLE.

 

Downloads

Download data is not yet available.

References

Keerthana PC, Anila KN. Carbamazepine induced SLE-a rare and serious ADR. Int J Pharm Pharm Sci 2016;9(1):319-20.

Chng HH, Tan BE, Teh CL, Lian TY. Major gastrointestinal manifestations in lupus patients in Asia: Lupus enteritis, pseudo-obstruction, and protein-losing gastroenteropathy. Lupus 2000;19(12):1404-13.

Sunkureddi PR, Luu N, Xiao SY, Tang WW, Baethge BA. Eosinophilic enteritis with systemic lupus erythematosus. S Med J 2005;98:1049-52.

Pande I, Malaviya AN, Sekharan NG, Kailash S, Uppal SS, Kumar A. SLE in Indian men: Analysis of the clinical and laboratory features with a review of the literature. Lupus 1994;3:181-6.

Santiago M. Diarrhoea secondary to azathioprine in two patients with SLE. Lupus 1999;8:565.

Tian XP, Zhang X. Gastrointestinal involvement in systemic lupus erythematosus: Insight into pathogenesis, diagnosis and treatment. World J Gastroenterol 2010;16:2971-7.

Gornisiewicz M, Rodriguez M, Smith JK, Saag K, Alarcón GS. Protein-losing enteropathy in a young African-American woman with abdominal pain, diarrhea and hydronephrosis. Lupus 2001;10:835-40.

Mok CC, Ying KY, Mak A, To CH, Szeto ML. Outcome of protein-losing gastroenteropathy in systemic lupus erythematosus treated with prednisolone and azathioprine. Rheumatology (Oxford) 2006;45(4):425-9.

Zheng WJ, Tian XP, Li L, Jing HL, Li F, Zeng XF, et al. Protein-losing enteropathy in systemic lupus erythematosus: Analysis of the clinical features of fifteen patients. J Clin Rheumatol 2007;13:313-6.

Kim YG, Lee CK, Byeon JS, Myung SJ, Oh JS, Nah SS, et al. Serum cholesterol in idiopathic and lupus-related protein-losing enteropathy. Lupus 2008;17:575-9.

Published

01-07-2017

How to Cite

H, S., H. M, N. Patil, K. Rao, B. Ommurugan, and S. Nayak B. “AN INTRIGUING CAUSE OF CHRONIC DIARRHEA – PROTEIN-LOSING ENTEROPATHY AS THE PRESENTING MANIFESTATION OF SYSTEMIC LUPUS ERYTHEMATOSUS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 7, July 2017, pp. 11-12, doi:10.22159/ajpcr.2017.v10i7.18880.

Issue

Section

Case Study(s)

Most read articles by the same author(s)

1 2 3 4 > >>