STANDARDIZATION OF SIDDHA HERBOMINERAL FORMULATION LINGA MATHIRAI

Abstract

 Objective: Linga Mathirai is traditional Siddha medicine. The medicinal plants and the herbal preparations are preferred; nowadays, due to minimal side effects and the presence of abundant antioxidants and micronutrients which possesses a better therapeutic efficiency. According to the World Health organization, the herbal medicines have been defined as those containing plant parts or plant materials in raw state or processed form containing active principles. The Siddha system of medicine encompasses around 600 medicinal plants in materia medica.

Methods: Physicochemical analysis such as pH, ash values, and loss on drying is done and biochemical analysis of acid and basic radicals. Instrumental analysis of Fourier transform-infrared (FT-IR) for analyze the functional groups in the test drug, scanning electron microscope (SEM) for determine the particle size of the drug, and inductively coupled plasma-optic emission spectrometry (ICP-OES) for heavy metal analysis.

Result: For standardization, organoleptic characters were done in that pH is 7.6, ash value is 1.379%, water-soluble ash is 0.294%, acid-insoluble ash is 0.871%, loss on drying in 105 is 0.483%, and disintegration time is 23 min. The functional group were analyzed by FT-IR. Then, in SEM, it has nano and microparticles. Finally, in ICP-OES, heavy metals are in permissible limits.

Conclusion: This standardization helps this drug to develop in future and also to evaluate these drug scientifically by determine the toxicity of the drug and pharmacological effect.