ANALYSIS OF BIOLOGICAL ACTIVITY AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY STUDY OF CONVENTIONAL EXTRACTION OF VITEX NEGUNDO LINN. LEAVES

Samreen Fatema; Milind Ubale; Mazahar Farooqui; Pathan Mohd Arif

doi:10.22159/ajpcr.2019.v12i1.27854

Authors

Samreen Fatema Department of Chemistry, Maulana Azad College, Aurangabad, Maharashtra, India.
Milind Ubale Department of Chemistry, Vasantrao Naik College, Aurangabad, Maharashtra, India.
Mazahar Farooqui Department of Chemistry, Dr. Rafiq Zakaria College for Women, Navkhanda, Aurangabad, Maharashtra, India.
Pathan Mohd Arif Department of Chemistry, Maulana Azad College, Aurangabad, Maharashtra, India. http://orcid.org/0000-0001-8402-3450

DOI:

https://doi.org/10.22159/ajpcr.2019.v12i1.27854

Keywords:

Vitex negundo, Antioxidant activity, Gas chromatography-mass spectrometry study, Aqueous extraction

Abstract

Objective: The main objective of the present work is to carry out the biological activity, gas chromatography-mass spectrometry (GC-MS) studies for the possible compounds present in Vitex negundo.

Methods: The aqueous extract of V. negundo Linn. was screened for biological activities such as antimicrobial, antituberculosis (TB), antimalarial, and antioxidant activities. The GC-MS analysis was carried out.

Results: The result shows that leaf extract is effective against Escherichia Coli and Bacillus subtitus while negative results for anti-TB and anti-malarial activity. The antioxidant activity of the leave extract is excellent.

Conclusion: The compounds present in the leaf extract of V. negundo are responsible for possessing the biological activity.

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Author Biographies

Samreen Fatema, Department of Chemistry, Maulana Azad College, Aurangabad, Maharashtra, India.

department of chemistry

Pathan Mohd Arif, Department of Chemistry, Maulana Azad College, Aurangabad, Maharashtra, India.

ASSOCIATE PROFESSOR, AND

INCHARGE, POST GRADUATE AND RESEARCH CENTRE, Maulana Azad College, Aurangabad (MS), India 431001

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