THE EFFECTIVENESS OF GIVING SNAIL SLIME (ACATINA FULICA) ON THE HEALING OF POCKET ON THE WISTAR RATS WITH PERIODONTITIS
DOI:
https://doi.org/10.22159/ijap.2019v11si2.35281Keywords:
Snail slime, Pocket, PeriodontitisAbstract
Objective: Periodontitis is an inflammatory disease of dental support tissue caused by certain groups of microorganisms, resulting in progressive destruction of the periodontal ligament and alveolar bone, with pocket formation, recession, or both. Snail slime contains beta-agglutinin (antibody) in plasma (serum), achacin protein, glycoconjugate and sulphate acting, which play a role in the wound healing process by assisting blood clotting process and fibroblast proliferation. This study aims to prove that the provision of snail slime can cure pocket in wistar rats with periodontitis.
Methods: This type of research is an experimental test with pre and post test control group design and involves three treatment groups, each group with five subjects. The first group of debridement, the second group of debridement and orally snail slime and the third group of debridement and topically snail slime, previously rats as subjects were conditioned to periodontitis by the installation of silk ligature in the cervical area of the incisors and injection with actinobacillus actinomycetemcomitans bacteria. The pocket depth is checked with a periodontal probe. Examination on day 11 occurs chronic periodontitis. The eighth day after treatment was examined on the periodontal pocket.
Results: The first group occurred a reduction in pocket depth from 3 mm to 1,00 mm, while in the second group periodontitis healing was characterized by the absence of a pocket, the third group still had pockets with a depth of 0.5 mm. Analysis of significance data using Kruskal-Wallis test, then Mann-Whitney test to know the differences between groups, The average pocket depth in group 1 was 0.00±1.00, while in group 2 was 0.00±0.00, and group 3 was 0.00±0.5 p-value = 0.001 this mean different healing significantly (p<0.05).
Conclusion: Provision of peroral snail slime more quickly cure pocket in wistar rats with periodontitis.
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References
2. Ireland R. Clinical textbook of dental hygiene and therapy. 1st ed. UK: Blackwell Munksgaard; 2006. p. 75-82.
3. Brooks I. Microbiology and management of periodontal infections. Gen Dent 2003;51:424-8.
4. Greenstain G. Nonsurgical periodontal therapy in 2000. A literature review. J Am Dent Assoc 2000;131:1580-92.
5. Muhavit A, Afriwardi, Fitriani A. Uji daya antioksidan ekstrak gambir (Uhcaria Gambir Roxb) pada saliva periodontitis kronis; 2016.
6. Oroh GC, Pangemanan DHC, Mintjelungan NC. Efektivitas lendir bekicot (Achatina fulica) terhadap jumlah sel fibroblas pada luka pasca pencabutan gigi tikus wistar, Jurnal e-Gigi (eG); 2015. p. 3.
7. Cruz MC, Sanz Rodriguez F, Zamarron A, Reyes E, Carrasco E, Gonzalez S. A secretion of the mollusc Cryptomphalus aspersa promotes proliferation, migration and survival of keratinocytes and dermal fibroblasts in vitro. Int J Cosmet Sci 2012;34:183-9.
8. Swastini IGAAP. Inhibitory power of snail mucus against actinobacillus actinomycetemcomitans bacteria. The research was conducted at Airlangga University Microbiology Research Center Surabaya; 2017.
9. Asdar. Pengaruh propolis terhadap kolagenisasi pada proses penyembuhan luka subkutan punggung mencit yang diinduksi bakteri actinobacillus actinomycetemcomicans. J Dentomaxillofac Sci 2012;1:2.
10. Herryawan. Effect of topical application red betel (piper crocatum) leaf gel on clinical attachment level repair patient with chronic periodontitis. J Dentomaxillofac Sci 2017;2:160-3.
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Copyright (c) 2019 SWASTINI IGAAP, PUTRA MANUABA I. B., HASANUDDIN THAHIR, RAKA SUDEWI A. A, BAKTA I. MD, MANTIK A. I NYM, SUKRAMA ID MD, SUTIRTAYASA IWP, MAHADEWA TGB
This work is licensed under a Creative Commons Attribution 4.0 International License.
