TY - JOUR AU - Shabrina, Mauldina AU - Suniarti, Dewi Fatma AU - Amir, Lisa R AU - Idrus, Erik PY - 2017/10/30 Y2 - 2024/03/29 TI - TOXICITY ANALYSIS OF RGD-CHITOSAN FROM SHRIMP SHELL SCAFFOLD MEMBRANES TOWARD HUMAN DENTAL PULP CELLS JF - International Journal of Applied Pharmaceutics JA - Int J App Pharm VL - 9 IS - 0 SE - Original Article(s) DO - 10.22159/ijap.2017.v9s1.07_08 UR - https://journals.innovareacademics.in/index.php/ijap/article/view/23284 SP - 13-16 AB - <p><strong>Objective:</strong> This study aimed to analyze RGD-Chitosan from Shrimp Shells' Scaffolds' (RCSSS) and CSSS membrane toxicity toward human dental pulp<br />cells.<br /><strong>Methods:</strong> Human dental pulp cells were cultured for 5 days and then exposed to RCSSS or CSSS membranes for 24 hrs. Cell viability was determined<br />using an MTT assay method.<br /><strong>Results:</strong> Cell viability of the RCSSS group and CSSS group was higher than the cell viability of the control group. The cell viability of the RCSSS<br />group 2 mg (537.39%) was significantly higher than the CSSS group 2 mg (301.74%).<br /><strong>Conclusions:</strong> RCSSS membranes were not toxic toward human dental pulp cells and showed better effect toward human dental pulp cells compared<br />to CSSS membranes.</p> ER -