A REVIEW ON RECENT ADVANCEMENT IN PULSATILE DRUG DELIVERY SYSTEMS
DOI:
https://doi.org/10.22159/ijcpr.2021v13i2.41543Keywords:
Circadian, Pulsatile, Drug delivery, AdvancementAbstract
Delivery systems with a pulsatile-release method are particularly involved in designing medicines for which traditional managed drug-release systems with the continuous release are not suitable. This medication also has a high first-pass impact or special conditions for chrono-pharmacology. These medications also have a high first-pass or unique chronopharmacological effect. The pulsatile release profile is characterised by a duration of no release (lag time) followed by a fast and full release of the drug. Pulsatile drug delivery systems may be classified into site-specific systems in which the drug is released inside the gastrointestinal system (e. g. colon) or time-controlled devices wherein the drug is released after a well-defined time period. Site-regulated release is typically controlled by environmental factors, such as pH or enzymes found in the intestinal tract, whereas drug release from time-controlled processes is controlled mainly by the delivery system and, preferably, not by the environment. This review covers various single-and multiple-unit oral pulsatile drug-delivery systems with an emphasis on time-controlled drug-release systems.
Downloads
Download data is not yet available.
References
1. Gandhi BR, Mundada AS, Gandhi PP. Chronopharmaceutics: as a clinically relevant drug delivery system. Drug Delivery 2011;18:1-18.
2. Amit K, Sonam R. Pulsatile drug delivery system: method and technology review. Int J Drug Dev Res 2012;4:95-107.
3. Aschoff J, Gerecke V, Wever R. Desynchronisation of human circadian rhythms. Japan J Physiol 1967;17:450–7.
4. James A. Physiological functions showing circadian rhythm: Circadian Rhytham; 2018. p. 1-4.
5. Brandenberger G, Charloux A, Gronfier C, Otzenberger H. Ultradian rhythms in hydromineral hormones. Horm Res 1998;49:131-5.
6. Crison J, Siersna PR, Taylor MD, Amidon GL. Control release bioact mater. 1995;22:278.
7. Soutar S, Stevens HNE, Mahony BO. Proc Int Symp Controlled Release Bioact Mater. Bioact Mater 2001;28:790.
8. Shweta A, Ali J, Ahuja A, Sanjula B, Javed Q. Pulsatile drug delivery systems: an approach for controlled drug delivery. Indian J Pharm Sci 2006;68:295-300.
9. Patel VR, Patel PV. P pulsatile drug delivery system. Int J Pharm Sci Res 2015;5:3676-88.
10. Hebden JM, Wilson CG, Spiller RC, GilChrist PJ, BlackShaw PE, Frier M, et al. Regional differences in quinine absorption from the undisturbed human colon assessed using a timed release delivery system. Pharm Res 1999;16:1087-92.
11. Burns JS, Stevens HNE, McEwen J, Pritchard G, Brewer FM, Clarke A, Johnsons ES, et al. Development of efficient acid cleavable multifunctional prodrugs derived from dendritic polyglycerol with a poly(ethylene glycol) shell. J Controlled Release 1996;38:151.
12. Bussemer T, Dashevsky A, Bodmeier R. A pulsatile drug delivery system based on rupturable coated hard gelatin capsules. J Controlled Release 2003;93:331.
13. Mohamad A, Dashevsky A. pH-independent pulsatile drug delivery system based on hard gelatin capsules and coated with aqueous dispersion Aquacoat ECD. Eur J Pharm Biopharm 2006;64:173-9.
14. Roy P, Shahiwala A. Multiparticulate formulation approach to pulsatile drug delivery: current perspectives. J Controlled Release 2009;134:74-80.
15. Rompicharla B, Prabha KS, Tabasum Md. A comprehensive review of pulsatile drug delivery system. Int Res J Pharm 2012;3:106-8.
16. Amit K, Sonam R. Pulsatile drug delivery system: method and technology review. Int J Drug Dev Res 2012;4:95-107.
17. Rasve G, Borade G, Deshmukh S, Tagalpallewar A. Pulsatile drug delivery system: current scenario. Int J Pharma Bio Sci 2011;2:332-43.
18. Suthar M, Patel U, Brahm Bhatt T, Patel H. Pulsatile drug delivery: a review. Int J Pharm Res Bio Sci 2007;1:3-12.
19. Tajane SR, Kholwal BB, Suryawanshi SS, Tarkase KN. Current trends in pulsatile drug delivery system. Int J Pharm Sci Res 2012;3:358-63.
20. Singh DK, Poddar AS, Nigade SU, Poddar SS. Pulsatile drug delivery system: an overview. Int J Curr Pharm Rev Res 2011;2:55-80z.
21. D’Souza, Sutar KP, Sutar PS, Nadgouda S. The use of chronotherapeutics in design of pulsatile delivery system-a review. J Pharm Sci Innovation 2012;2:50-5.
22. Vinupama S, Shwetha S, Kamath K, Keerthi TS. Pulsatile drug delivery system: a review. Int Bull Drug Res 2012;1:19-31.
23. Gajbhiye ND, Vilasrao JK, Kisan RJ, Anand UK. Pulsatile drug delivery system. J Pharm Res 2010;2:120-3.
24. Singh Anamika, Dubey Harikesh, Shukla Indu, Singh Dharmchand P. Pulsatile drug delivery system: an approach of medication according to circadian rhythm. J Appl Pharm Sci 2012;2:166-76.
25. Singh A, Dubey H, Shukla I, Singh DP. Pulsatile drug delivery system: an approach of medication according to circulation rhythm. J Appl Pharm Sci 2012;2:166-76.
26. Rajput M, Sharma R, Kumar S, Jamil F, Sissodia N. Pulsatile drug delivery system: a review. Int J Res Pharm Biomed Sci 2012;3:118-22.
27. Kumar GA, Bhat A, Lakshmi AP, Reddy K. An overview of stimuli–induced pulsatile drug delivery system. Int J Pharm Tech Res 2010;2:3658-2375.
28. Kanchan Mandal M, Joshi AL, Raval A, Patel YK. Pulsatile drug delivery-a better chronothepy system: a review. World J Pharm Res 2018;7:690-705.
29. Harikeshn D. Pulsatile drug delivery system: an approach of medication according to circadian rhythm. J Appl Pharm Sci 2018;2:166-76.
30. Suresh R. Design, development and evaluation of press coated tablets of an eprosartan mesylate. Bull Pharm Med Sci 2014;2:2347-55.
31. Chourasia MK, Jain SK. Pharmaceutical approaches to colon targeted drug delivery systems. J Pharm Pharm Sci 2003;6:33-66.
32. Kuotsu K, Nikhil B. Drug delivery system based on chronobiology-a review. J Controlled Release 2010;147:314–25.
33. Vipul PP, Soniwala Moinuddin M. Pulsatile drug delivery system for treatment of various inflammatory disorders-a review. Int J Drug Dev Res 2012;4:67-87.
34. Modasiya Moin K, Vishnu PM. Pulsatile drug delivery system for colon–a review. Int J Res Pharm Biomed Sci 2011;2:934-41.
35. Pandit V, Kumar A, Ashawat MS, Verma CP, Kumar P. Recent advancement and technological aspects of pulsatile drug delivery system-a laconic review. Curr Drug Targets 2017;18:1191-203.
36. Patwekar SL, Baramade MK. Controlled release approach to novel multiparticulate drug delivery system. Int J Pharm Pharm Sci 2012;4:756-63.
37. Ravula AN, Goud BA. Recent advances in oral pulsatile drug delivery. J Adv Pharm Sci 2011;1:57-62.
38. Rosenmayr Templeton L. The elan of delivery technology development. Int Association for Pharmaceutical Technology Newsletter; 2011. p. 2.
39. Dey NS, Majumdar S, Rao MEB. Multiparticulate drug delivery systems for controlled release. Trop J Pharm Res 2008;7:1067-75.
40. Shidhaye S, Dhone A, Budhkar T, Surve C. Technologies in pulsatile drug delivery system. Int J Adv Pharm Biol Chem 2012;1:438-45.
41. Kalantzi LE, Karavas E, Koutris EX, Bikiaris DN. Recent advances in oral pulsatile drug delivery. Recent Pat Drug Delivery Formul 2009;3:49-63.
42. Wani SUD, Gangadharappa HV, Ashish PN. Formulation, development and characterization of drug delivery systems based telmisartan encapsulated in silk fibroin nanosphere’s. Int J Appl Pharm 2019;11:247-54.
2. Amit K, Sonam R. Pulsatile drug delivery system: method and technology review. Int J Drug Dev Res 2012;4:95-107.
3. Aschoff J, Gerecke V, Wever R. Desynchronisation of human circadian rhythms. Japan J Physiol 1967;17:450–7.
4. James A. Physiological functions showing circadian rhythm: Circadian Rhytham; 2018. p. 1-4.
5. Brandenberger G, Charloux A, Gronfier C, Otzenberger H. Ultradian rhythms in hydromineral hormones. Horm Res 1998;49:131-5.
6. Crison J, Siersna PR, Taylor MD, Amidon GL. Control release bioact mater. 1995;22:278.
7. Soutar S, Stevens HNE, Mahony BO. Proc Int Symp Controlled Release Bioact Mater. Bioact Mater 2001;28:790.
8. Shweta A, Ali J, Ahuja A, Sanjula B, Javed Q. Pulsatile drug delivery systems: an approach for controlled drug delivery. Indian J Pharm Sci 2006;68:295-300.
9. Patel VR, Patel PV. P pulsatile drug delivery system. Int J Pharm Sci Res 2015;5:3676-88.
10. Hebden JM, Wilson CG, Spiller RC, GilChrist PJ, BlackShaw PE, Frier M, et al. Regional differences in quinine absorption from the undisturbed human colon assessed using a timed release delivery system. Pharm Res 1999;16:1087-92.
11. Burns JS, Stevens HNE, McEwen J, Pritchard G, Brewer FM, Clarke A, Johnsons ES, et al. Development of efficient acid cleavable multifunctional prodrugs derived from dendritic polyglycerol with a poly(ethylene glycol) shell. J Controlled Release 1996;38:151.
12. Bussemer T, Dashevsky A, Bodmeier R. A pulsatile drug delivery system based on rupturable coated hard gelatin capsules. J Controlled Release 2003;93:331.
13. Mohamad A, Dashevsky A. pH-independent pulsatile drug delivery system based on hard gelatin capsules and coated with aqueous dispersion Aquacoat ECD. Eur J Pharm Biopharm 2006;64:173-9.
14. Roy P, Shahiwala A. Multiparticulate formulation approach to pulsatile drug delivery: current perspectives. J Controlled Release 2009;134:74-80.
15. Rompicharla B, Prabha KS, Tabasum Md. A comprehensive review of pulsatile drug delivery system. Int Res J Pharm 2012;3:106-8.
16. Amit K, Sonam R. Pulsatile drug delivery system: method and technology review. Int J Drug Dev Res 2012;4:95-107.
17. Rasve G, Borade G, Deshmukh S, Tagalpallewar A. Pulsatile drug delivery system: current scenario. Int J Pharma Bio Sci 2011;2:332-43.
18. Suthar M, Patel U, Brahm Bhatt T, Patel H. Pulsatile drug delivery: a review. Int J Pharm Res Bio Sci 2007;1:3-12.
19. Tajane SR, Kholwal BB, Suryawanshi SS, Tarkase KN. Current trends in pulsatile drug delivery system. Int J Pharm Sci Res 2012;3:358-63.
20. Singh DK, Poddar AS, Nigade SU, Poddar SS. Pulsatile drug delivery system: an overview. Int J Curr Pharm Rev Res 2011;2:55-80z.
21. D’Souza, Sutar KP, Sutar PS, Nadgouda S. The use of chronotherapeutics in design of pulsatile delivery system-a review. J Pharm Sci Innovation 2012;2:50-5.
22. Vinupama S, Shwetha S, Kamath K, Keerthi TS. Pulsatile drug delivery system: a review. Int Bull Drug Res 2012;1:19-31.
23. Gajbhiye ND, Vilasrao JK, Kisan RJ, Anand UK. Pulsatile drug delivery system. J Pharm Res 2010;2:120-3.
24. Singh Anamika, Dubey Harikesh, Shukla Indu, Singh Dharmchand P. Pulsatile drug delivery system: an approach of medication according to circadian rhythm. J Appl Pharm Sci 2012;2:166-76.
25. Singh A, Dubey H, Shukla I, Singh DP. Pulsatile drug delivery system: an approach of medication according to circulation rhythm. J Appl Pharm Sci 2012;2:166-76.
26. Rajput M, Sharma R, Kumar S, Jamil F, Sissodia N. Pulsatile drug delivery system: a review. Int J Res Pharm Biomed Sci 2012;3:118-22.
27. Kumar GA, Bhat A, Lakshmi AP, Reddy K. An overview of stimuli–induced pulsatile drug delivery system. Int J Pharm Tech Res 2010;2:3658-2375.
28. Kanchan Mandal M, Joshi AL, Raval A, Patel YK. Pulsatile drug delivery-a better chronothepy system: a review. World J Pharm Res 2018;7:690-705.
29. Harikeshn D. Pulsatile drug delivery system: an approach of medication according to circadian rhythm. J Appl Pharm Sci 2018;2:166-76.
30. Suresh R. Design, development and evaluation of press coated tablets of an eprosartan mesylate. Bull Pharm Med Sci 2014;2:2347-55.
31. Chourasia MK, Jain SK. Pharmaceutical approaches to colon targeted drug delivery systems. J Pharm Pharm Sci 2003;6:33-66.
32. Kuotsu K, Nikhil B. Drug delivery system based on chronobiology-a review. J Controlled Release 2010;147:314–25.
33. Vipul PP, Soniwala Moinuddin M. Pulsatile drug delivery system for treatment of various inflammatory disorders-a review. Int J Drug Dev Res 2012;4:67-87.
34. Modasiya Moin K, Vishnu PM. Pulsatile drug delivery system for colon–a review. Int J Res Pharm Biomed Sci 2011;2:934-41.
35. Pandit V, Kumar A, Ashawat MS, Verma CP, Kumar P. Recent advancement and technological aspects of pulsatile drug delivery system-a laconic review. Curr Drug Targets 2017;18:1191-203.
36. Patwekar SL, Baramade MK. Controlled release approach to novel multiparticulate drug delivery system. Int J Pharm Pharm Sci 2012;4:756-63.
37. Ravula AN, Goud BA. Recent advances in oral pulsatile drug delivery. J Adv Pharm Sci 2011;1:57-62.
38. Rosenmayr Templeton L. The elan of delivery technology development. Int Association for Pharmaceutical Technology Newsletter; 2011. p. 2.
39. Dey NS, Majumdar S, Rao MEB. Multiparticulate drug delivery systems for controlled release. Trop J Pharm Res 2008;7:1067-75.
40. Shidhaye S, Dhone A, Budhkar T, Surve C. Technologies in pulsatile drug delivery system. Int J Adv Pharm Biol Chem 2012;1:438-45.
41. Kalantzi LE, Karavas E, Koutris EX, Bikiaris DN. Recent advances in oral pulsatile drug delivery. Recent Pat Drug Delivery Formul 2009;3:49-63.
42. Wani SUD, Gangadharappa HV, Ashish PN. Formulation, development and characterization of drug delivery systems based telmisartan encapsulated in silk fibroin nanosphere’s. Int J Appl Pharm 2019;11:247-54.
Published
15-03-2021
How to Cite
THAKUR, G., S. U. D. WANI, and S. P. GAUTAM. “A REVIEW ON RECENT ADVANCEMENT IN PULSATILE DRUG DELIVERY SYSTEMS”. International Journal of Current Pharmaceutical Research, vol. 13, no. 2, Mar. 2021, pp. 6-10, doi:10.22159/ijcpr.2021v13i2.41543.
Issue
Section
Review Article(s)
