EVALUATION OF CAFFEINE CONSUMPTION AND EFFECT DURING PREGNANCY AMONG WOMEN IN THE UAE

Authors

  • Muaed Jamal Alomar Ajman University of Science and Technology

Keywords:

Caffeine, Pregnant, Abortion, Miscarriage

Abstract

Objective: To investigate the relationship between caffeine consumption among pregnant women in the UAE and spontaneous abortion and stillbirth.

Methods: A retrospective cross-sectional survey has been conducted on 97 pregnant ladies randomly selected from Al Ain city in the UAE. Only pregnant women with caffeine intake were included in the study.

Results: The results showed that: 61.9% of women consumed coffee, 34% consumed tea, and 4.1% consumed soft drinks during pregnancy. 43% of women who consumed caffeine during pregnancy had at least one spontaneous abortion, 10.3% suffered from stillbirth and 17.5% gave birth to underweight babies. Cross tabulation between spontaneous abortion and caffeine consumption did not show high significance using Pearson Chi-Square for correlation (p-value 0.103), The likelihood ratio shows significant results (p-value 0.039).

Conclusion: Providing comprehensive counselling for pregnant women is essential in order to prevent the negative impact of caffeine consumption.

Keywords: Caffeine, Pregnant, Abortion, Miscarriage

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References

Kirkinen P, Jouppila P, Koivula A, Vuori J, Puukka M. The effect of caffeine on placental and fetal blood flow in human pregnancy. Am J Obstet Gynecol 1983;147:939-42.

Aldridge A, Bailey J, Neims AH. The disposition of caffeine during and after pregnancy. Seminars Perinatol 1981;5:310-4.

Weathers bee PS, Olsen LK, Lodge JR. Caffeine and pregnancy. A retrospective survey. Postgrad Med 1977;62:64-9.

Wichit S, Bracken MB. Caffeine consumption during pregnancy and association with late spontaneous abortion. Am J Obstet Gynecol 1986;154:14–20.

Weng X, Odouli R, Li DK. Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study. Am J Obstet Gynecol 2008;198:279 e1-e8.

Chen LW, Wu Y, Neelakantan N, Chong MF, Dam RM, Pan A. Maternal caffeine intake during pregnancy and risk of pregnancy loss: a categorical and dose–response meta-analysis of prospective studies. Public Health Nutr 2015;19:1-12.

Andrews KW, Schweitzer A, Zhao C, Holden JM, Roseland JM, Brandt M, et al. The caffeine contents of dietary supplements commonly purchased in the US: Analysis of 53 products with caffeine-containing ingredients. Anal Bioanal Chem 2007;389:231–9.

Regan L, Bailey LG, Jaime J, Johanna T. Estimating caffeine intake from energy drinks and dietary supplements in the United States. Nutr Rev 2014;72:9–13.

Kenneth SK, Carol AP. Caffeine intake, tolerance, and withdrawal in women: a population-based twin study. Am J Phychiatry 1999;156:223-8.

Molloy JW, Calcagno CJ, Williams CD, Jones FJ, Dawn M. Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis. Hepatology 2012;55:429-36.

Hahn KA, Wise LA, Rothman KJ, Mikkelsen EM, Brogly SB, Sørensen HT, et al. Caffeine and caffeinated beverage consumption and risk of spontaneous abortion. Hum Reprod 2015;30:1246-55.

Howards PP, Picciotto JH, Bech BH, Nohr EA, Andersen AMN, Poole C, et al. Spontaneous abortion and a diet drug containing caffeine and ephedrine: a study within the danish national birth cohort. PLOS One 2012;7:1-12.

Sims MA, Collins KA, Melissa A, Kim A. Fetal death: a 10-year retrospective study. Am J Forensic Med Pathol 2001;22:261–5.

Garcıa-Engu Ì Ä±danos A, Calle ME, Valero J Ì, Luna S. Risk factors in miscarriage: a review. Eur J Obstet Gynecol Reprod Biol 2002;102:111–9.

Li J, Zhao H, Song JM, Zhang J, Tang YL, Xin CM. A meta-analysis of the risk of pregnancy loss and caffeine and coffee consumption during pregnancy. Int J Gynecol Obstet 2015;130:116-22.

Maslova E, Bhattacharya S, Lin SW, Michels KB. Caffeine consumption during pregnancy and risk of preterm birth: a meta-analysis. Am J Clin Nutr 2010;92:1120–32.

Eteng MU, Eyong EU, Akpanyung EO, Agiang MA, Aremu CY. Recent advances in caffeine and theobromine toxicities: a review. Plant Foods Hum Nutr 1997;51:231–43.

Aldridge A, Aranda JV, Neims AH. Caffeine metabolism in the newborn. Clin Pharmacol Ther 1979;25:447–53.

Sengpiel V, Elind E, Bacelis J, Nilson S, Grove J. Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study. BMC Med 2013;11:42.

Kirkinen P, Jouppila P, Koivula A, Vuori J, Pukka M. The effect of caffeine on placental and fetal blood flow in human pregnancy. Am J Obstet Gynecol 1983;147:939–42.

Peck JD, Leviton A, Cowan LD. A review of the epidemiologic evidence concerning the reproductive health effects of caffeine consumption: a 2000–2009 update. Food Chem Toxicol 2010;48:2549–76.

Greenwood DC, Thatcher NJ, Garrard L, Keogh G, King LG, Cade J. Caffeine intake during pregnancy and adverse birth outcomes: a systematic review and dose–response meta-analysis. Eur J Epidemiol 2014;29:725-34.

Sengpiel V, Elind E, Bacelis J, Nilsson S, Grove J, Myhre R. Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study. BMC Med 2013;11:42.

Li DK, Ferber JR, Odouli R. Maternal caffeine intake during pregnancy and risk of obesity in offspring: a prospective cohort study. Int J Obes 2015;39:658-64.

Kolnes AJ, Ingvaldsen A, Bolling A, Stuenaes JT, Kreft M, Zorec R, et al. Caffeine and theophylline block insulin-stimulated glucose uptake and PKB phosphorylation in rat skeletal muscles. Acta Physiol (Oxf) 2010;200:65–74.

Peck JD, Leviton A, Cowan LD. A review of the epidemiologic evidence concerning the reproductive health effects of caffeine consumption: a 2000–2009 update. Food Chem Toxicol 2010;48:2549–76.

Chen LW, Wu Y, Neelakantan N, Chong MFF, Dam RV. Maternal caffeine intake during pregnancy is associated with risk of low birth weight: a systematic review and dose–response meta-analysis. BMC Med 2014;12:174.

Published

01-06-2016

How to Cite

Alomar, M. J. “EVALUATION OF CAFFEINE CONSUMPTION AND EFFECT DURING PREGNANCY AMONG WOMEN IN THE UAE”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 8, no. 6, June 2016, pp. 101-3, https://journals.innovareacademics.in/index.php/ijpps/article/view/10761.

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