PHYTOCHEMICAL SCREENING AND STANDARDIZATION OF POLYHERBAL FORMULATION: MAHARISHI AMRIT KALASH 5

Authors

  • Chitra R. Kamath Department of Chemistry, K.J. Somaiya College of Arts, Science and Commerce, Vidyanagar, Vidyavihar, Mumbai 400077
  • Bhavini Shah Department of Chemistry, K.J. Somaiya College of Arts, Science and Commerce, Vidyanagar, Vidyavihar, Mumbai 400077

Keywords:

MAK-5, Polyherbal, Organoleptic, Phytoconstituents, Standardization, Physicochemical

Abstract

Objective: The main aim of the study was to standardize the polyherbal formulation on the basis of organoleptic characters, phytochemical analysis, physicochemical parameters and fluorescence analysis.

Methods: All the above tests were performed based on WHO norms.

Results: Organoleptic characters revealed that formulation was light brown in color, characteristic odor, bitter in taste and moderately fine texture. Physicochemical parameters resulted in water soluble extractive (35.8 ± 0.35), alcohol soluble extractive (38.6 ± 0.24), total ash (9.25 ± 0.12), acid insoluble ash (1.94 ± 0.23), water soluble ash (6.5 ± 0.18), pH (7.49 ± 0.02), crude fat (0.3 ± 0.1), LOD at 1050C (7.2 ± 0.6) and moisture content (6.2 ± 0.8). Phytochemical analysis shows the presence of alkaloids, tannins, flavonoids, steroids, terpenoids, etc. Fluorescence analysis of formulation was studied using different chemical reagents.

Conclusion: The in-house formulation was prepared and screened for various standardization parameters as per ayurvedic pharmacopoeial standards.

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References

Satheesh NV, Kumud U, Asha B. Phytochemical screening and standardization of poly herbal formulation for Dyslipidemia. Int J of Pharmacy and Pharm Sci 2011;3 (Suppl 3):235-38.

Organisation Mondiale De La Sante, Quality control methods for medicinal plant materials, 559, rev.1, Original English, World Health Organisation;1992. p. 159.

Ozarkar KR. Studies on antiâ€inflammatory effects of two herbs Cissusquadrangularis Linn. and Valeriana wallichi DC using mouse model. Ph.D. Thesis, University of Mumbai, Mumbai 2005.

Maharishi ayurveda [internet]. New Delhi:Maharishi Ayurveda Products Pvt. Ltd.;c2007 [updated 2013 Oct 12;cited 2012 Jan 14]. Available from http:// www. Maharishi ayurveda india. Com /mak.php

Siddiqui, Hakim MA. Format for the pharmacopoeial analytical standards of compoundformulation, Workshop on standardization of Unani drugs, (appendix)New Delhi:Central Council for Research in Unani Medicine (CCRUM);1995.Jan 24-25.

Anonymous. Quality Control Methods for Medicinal Plant Materials, World Health Organisation, Geneva;1998. p. 25â€28.

Harborne JB. Phytochemical Methods. Jackman H. (Ed.), London;1973. p. 70.

Kokate CK, Purohit AP and Gokhale SB. Pharmacognosy. 34th Edn. Nirali Prakashan, Pune, India;2006.

Mukherjee PK. Quality control of herbal drugs, I edition, Business horizons publishers;2002. p. 195â€196.

Indrayan AK, Sharma S, Durgapal D, Kumar N, Kumar M. Determination of nutritive value and analysis of mineral elements for some medicinally valued plants from Uttaranchal. J Curr Sci 2005;89:1252â€55.

African Pharmacopoeia.General methods for analysis.1st edn.Vol. 2 (OAU/STRC) Lagos;1986. p.123.

Kamil MS, Paramjyothi S. Preliminary Pharmacognostical and Phytochemical Evaluation of Portulaca quadrifida Linn. Int J Pharm Tech Res 2010;2(3):1699â€1702.

Ansari SH. Essentials of Pharmacognosy. 1st Edn. New Delhi;Birla Publications Pvt. Ltd.;2006.

Published

01-07-2014

How to Cite

Kamath, C. R., and B. Shah. “PHYTOCHEMICAL SCREENING AND STANDARDIZATION OF POLYHERBAL FORMULATION: MAHARISHI AMRIT KALASH 5”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 6, no. 7, July 2014, pp. 96-98, https://www.innovareacademics.in/journals/index.php/ijpps/article/view/1268.

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