ANTIMICROBIAL AND ANTI-INFLAMMATORY STUDIES ON SARGASSUM WIGHTII EXTRACTS

Authors

  • Ramyapriyadharshini Raman Department of Biotechnology, School of Chemical & Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur 613401, Tamil Nadu, India
  • Sujitha Parthiban Department of Biotechnology, School of Chemical & Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur 613401, Tamil Nadu, India.
  • Karthikeyan S. Department of Biotechnology, Srimad Andavan Arts and Science College, Tiruchirapalli 620005, Tamil Nadu, India.
  • Meenakshi Sundaram Muthuraman Department of Biotechnology, School of Chemical & Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur 613401, Tamil Nadu, India.
  • Aravind Sivasubramanian Department of Chemistry, School of Chemical & Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur 613401, Tamil Nadu, India.

Keywords:

Antimicrobial, Anti-inflammatory, Sargassum wightii

Abstract

Objective: To evaluate the antimicrobial and anti-inflammatory effect of hexane, chloroform and ethanolic extract of Sargassum wightii.

Methods: Hexane, chlorofom and ethanolic extractions of these algae were done and evaluated for biological activity. Assay of antimicrobial activity was perfomed by disc diffusion method against various microorganisms. Assay of anti-inflammatory activity was performed in albino rats with paw edema, induced by Carrageenan.

Results: Chloroform and ethanol extracts exhibited antimicrobial activity against various microorganisms. All the extracts revealed anti-inflammatory activity, in which chloroform extract showed maximum activity in dose dependent manner.

Conclusions: Among the three different extracts tested, chloroform extract of S. wightii possess significant antimicrobial and anti-inflammatory activities. Further in-depth studies, could result in the development of a good antimicrobial and anti-inflammatory agent from this chloroform extract of S.wightii.

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References

Ali A. El Gamal. Biological importance of marine algae. Saudi Pharm J 2010;18:1-25.

Janakiraman M, Renisheya A, Petchiammal A. Johnson Babu Phytochemical characterization of brown seaweed Sargassum wightii. Asian Pacific J of Tropical Disease 2012:S109-S13.

SRC-GoogleScholar.

Dora M, Baja P. Yoloxochitl Elizabeth Rodríguez-Arvizu-Higuera and Gustavo Hernández-Carmona. Seasonal variation on size and chemical constituents of Sargassum sinicola Setchell et Gardner from Bahía de La Sur, Mexico. Phycological Res Br J Pharmacol 2008;56:33-8.

Tulay A, Fusun S. Rıza Antimicrobial Activities of Some Marine Algae and Some Cyanobacteria from Çanakkale (Turkey). J of Algal Biomass Utilisation Br J Pharmacol 2013;4(3):35-40.

Ferda F. Zeliha Demirel, Yilmaz-koz, Ulku n. Karabayyavasoglu Guven ozdemir and Atakan sukatar Antimicrobial and antioxidant activity of brown algae from the aegean sea J of Serbian Chemical Society 2009;74(6):619-28.

Kadarkarai K, Arjunan K, Jiang-Shiou K, Donald R. Kanagarajan Prasanna Kalimuthu Barnardc. Combined effect of seaweed Sargassum wightii and Bacillus thuringiensis var israelensis on the coastal mosquito Anopheles sundaicus. J Tamil Nadu India Sci Asia 2012;38:141-6.

Takia R, Pierre R, J. Bounar Messaoud and Gilles Feguiredo. Chemical composition and antibacterial activity of essential oil of Ziziphora hispanica l. J Global Med Plants Indigen Med 2013;2:73-80.

Zhi-Qiang S, Pamela S, David M, Margaret H, Pamela T. Daniela Wyatt, Bourdon, Marino, Manning Nitric oxide:a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br J Pharmacol 1996;118:829-38.

Yong Zhou, John F. Hancock, Lenard M. Lichtenberger. The Nonsteroidal Anti-Inflammatory Drug Indomethacin Induces Heterogeneity in Lipid Membranes:Potential Implication for Its. J Diverse Biological Action. PLoS ONE 2010;5:8811.

Perianayagam JB, Sharma SK, Pillai KK. Anti-inflammatory activity of Trichodesma indicum root extract in experimental animals. J Ethnopharmacol 2006;104(3):410-4.

Published

01-07-2014

How to Cite

Raman, R., S. Parthiban, K. S., M. S. Muthuraman, and A. Sivasubramanian. “ANTIMICROBIAL AND ANTI-INFLAMMATORY STUDIES ON SARGASSUM WIGHTII EXTRACTS”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 6, no. 7, July 2014, pp. 611-4, https://www.innovareacademics.in/journals/index.php/ijpps/article/view/1998.

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