GC-MS ANALYSIS OF BIOACTIVE CONSTITUENTS OF METHANOLIC EXTRACT OF LEAVES OF ACTINODAPHNE BOURDILLONII GAMBLE
Keywords:Actinodaphne bourdillonii, Terpene alcohol, Myirstic acid, Sugar moiety
Objective: The investigation was carried out to characterize the chemical constituents present in the methanolic extracts of leaves of Actinodaphne bourdillonii Gamble using GC-MS.
Methods: The chemical constituents of methanolic extract of A. bourdillonii were studied by using Perkin Elmer Gas Chromatography- Mass Spectroscopy.
Results: The GC-MS analysis of the methanolic extract revealed the presence of 18 compounds. The major chemical constituents are Tobacco compounds- 4,8,13-Cyclotetradecatriene-1,3-diol, 1,5,9-trimethyl-12-(1-methylethyl)- (33.47%), Terpene alcohol compounds - 3,7,11,15-Tetramethyl-2-hexadecen-1-ol (10.78%), Myirstic acid - Tetradecanoic acid (9.89%) and Sugar moiety compounds -1,6-Anhydro-2,4-dideoxy-Ã¡-D-ribo-hexopyranose (7.93%). The analysis of bioactive principles of methanolic extract of leaves of A. bourdillonii has not been reported previously.
Conclusion: A. bourdillonii is a valuable tree with numerous medicinal properties which contains various bioactive principles. Such studies will be very much help full in designing a new drugs for the therapeutic values.
Viswanathan MV, Unnikrishnan PM, Komatus K, Fushimi H, Basant P. A Brief introduction to Ayurvedic system of medicine and some of its problems. Indian J Traditional Knowledge 2003;2(2):159-69.
Koduru S, Grierson D S, Afolayan A. J Pharm Biol 2006;44:266-83.
Hema R, Kumaravel S, Elanchezhiyan N, Antimicrobial activity of some of the South-Indian spices and herbals against food pathogens. Global J Pharmacol 2009;3(1):38-40.
Burkill I, Birtwistle W. A dictionary of the economic products of the Malay Peninsula: Nature, Petaling Jaya; 1966. p. 255.
Basri DF, Fan SH. The potential of aqueous and acetone extracts of galls of Queercus infectoria as antibacterial agents. Indian J Pharmcol 2005;37:26â€“9.