THE BENEFICIAL EFFECT OF 20% SUNFLOWER SEED OIL CREAM ON MILD ATOPIC DERMATITIS IN CHILDREN

Authors

  • Reiva Farah Dwiyana Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia
  • Hartati Purbo Darmadji Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia
  • Risa Miliawati Nurul Hidayah Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia
  • Fitra Hergyana Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia
  • Srie Prihiantini Gondokaryono Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia
  • Inne Arline Diana Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia
  • Catherina Jessica Sutantoyo Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia
  • Hendra Gunawan Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia

DOI:

https://doi.org/10.22159/ijpps.2019v11i2.30707

Keywords:

Atopic dermatitis, Moisturizer, Sunflower seed oil, Transepidermal water loss

Abstract

Objective: The objective of this study was to evaluate the beneficial effect of topical applications of 20% sunflower seed oil (SSO) in decreasing the transepidermal water loss (TEWL) and scoring of atopic dermatitis (SCORAD) index value in mild atopic dermatitis (AD) pediatric patients in Bandung, Indonesia.

Methods: This was a randomized study involving 20 children with mild AD (SCORAD<25) in Bandung, Indonesia. They were divided into 2 groups: the experimental group treated with 20% SSO cream and the control group treated with a common moisturizing cream for four weeks. The TEWL score including SCORAD index was evaluated at baseline, week 1, week 2, and week 4.

Results: A total of 20 participants completed the study. In the first week, the control group had TEWL score decrement by 36.62% while the experimental group by 28.89% (p=0.88). In the fourth week, the TEWL decrements of the experimental and control group were by 56.94% and 52.50%, respectively (p=0.20), and this was followed by an improvement of SCORAD index in both treatment groups.

Conclusion: The 20% SSO cream has a beneficial effect in decreasing the TEWL score and improving SCORAD indices. Therefore, it can be considered as an alternative treatment for mild AD among children.

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Published

01-02-2019

How to Cite

Dwiyana, R. F., H. P. Darmadji, R. M. N. Hidayah, F. Hergyana, S. P. Gondokaryono, I. A. Diana, C. J. Sutantoyo, and H. Gunawan. “THE BENEFICIAL EFFECT OF 20% SUNFLOWER SEED OIL CREAM ON MILD ATOPIC DERMATITIS IN CHILDREN”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 11, no. 2, Feb. 2019, pp. 100-3, doi:10.22159/ijpps.2019v11i2.30707.

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Original Article(s)