• Sumanya H Department of Pharmacology, Faculty of Pharmacy, Sri Ramachandra University, Porur, Chennai, Tamil Nadu 600116
  • Lavanya R Department of Pharmacology, Faculty of Pharmacy, Sri Ramachandra University, Porur, Chennai, Tamil Nadu 600116
  • Umamaheswara Reddy C Department of Pharmacology, Faculty of Pharmacy, Sri Ramachandra University, Porur, Chennai, Tamil Nadu 600116


Caulerpa racemosa, Anti-oxidant, Diclofenac sodium, Anti-arthritic activity, Protein denaturation


Objective: The present study was aimed to evaluate in vitro anti-oxidant activity and in vitro anti arthritic activity of methanolic extract of Caulerpa racemosa.

Methods: The in vitro anti oxidant activity was evaluated by using following method viz; DPPH scavenging activity, Nitric oxide scavenging activity, Total anti-oxidant activity, Determination of reducing power. The in vitro anti arthritic activity was evaluated by using protein denaturation method.

Results: Methanolic extract of Caulerpa racemosa showed a very good anti-radical activity in scavenging DPPH radical and nitric oxide radical with maximum % inhibition of 88.87±1.05% at 2000μg/0.1 ml concentration and 80.49±1.43% at 2000μg/ml respectively. Total anti-oxidant activity and reducing power of Caulerpa racemosa was found to be 32μg equivalents of ascorbic acid at 500 μg/ml and 88.80±0.98% at 2000μg/0.05 ml respectively. The methanolic extract showed 49.33±0.597% of percentage inhibition at 1000μg/0.05 ml by protein denaturation method.

Conclusion: From the results obtained, it can be concluded that the methanolic extract of Caulerpa racemosa possesses significant anti-oxidant and anti-arthritic activity. Further studies are required to signify the mechanism of action of these pharmacological activities and to mark them out for their significant pharmacological actions.



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How to Cite

H, S., L. R, and U. R. C. “EVALUATION OF IN VITRO ANTI-OXIDANT AND ANTI-ARTHRITIC ACTIVITY OF METHANOLIC EXTRACT OF MARINE GREEN ALGAE CAULERPA RACEMOSA”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, no. 7, July 2015, pp. 340-3, https://www.innovareacademics.in/journals/index.php/ijpps/article/view/4283.



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