ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OF ARENGA WIGHTII GRIFF.-AN ENDEMIC PALM OF WESTERN GHATS

Authors

  • P Shikha Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Palode, Thiruvananthapuram 695562, India
  • P G Latha Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Palode, Thiruvananthapuram 695562, India
  • S R Suja Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Palode, Thiruvananthapuram 695562, India
  • S Rajasekharan Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Palode, Thiruvananthapuram 695562, India
  • G I Anuja Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Palode, Thiruvananthapuram 695562, India

Keywords:

Anti-inflammatory, Carrageenan-induced paw oedema, Cotton pellet-induced granuloma, Acetic acid-induced vascular permeability, Acetic acid-induced writhing, Formalin induced nociception, Acetyl salicylic acid, Indomethacin

Abstract

Objective: The present study aims to scientifically validate the anti-inflammatory and analgesic activities of Arenga wightii.

Methods: The stem pith was excised from mature palm, sliced into small pieces, shade dried and powdered. The powder was extracted with ethanol, concentrated under reduced pressure and the crude extract was referred to as AW. The anti-inflammatory and analgesic activity of AW was analyzed in Wistar rats and Swiss albino mice.

Results: The results revealed that the ethanolic extract of the stem pith of A. wightii showed a dose dependent anti-inflammatory and analgesic activity, which was comparable to the standards, indomethacin and acetyl salicylic acid respectively.

Conclusion: The results of the current study reveal that A. wightii possesses significant anti-inflammatory and analgesic activity.

 

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Published

01-07-2015

How to Cite

Shikha, P., P. G. Latha, S. R. Suja, S. Rajasekharan, and G. I. Anuja. “ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OF ARENGA WIGHTII GRIFF.-AN ENDEMIC PALM OF WESTERN GHATS”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, no. 7, July 2015, pp. 203-7, https://journals.innovareacademics.in/index.php/ijpps/article/view/5883.

Issue

Vol 7, Issue 7, 2015

Section

Original Article(s)