ESTIMATED DAILY INTAKE AND EXPOSURE OF SODIUM BENZOATE AND POTASSIUM SORBATE THROUGH FOOD PRODUCTS IN SCHOOL CHILDREN OF TIRUPATI, INDIA

Authors

  • M Vivek Reddy Mpharm student, Krishnateja pharmacy college, tirupathi india
  • G Aruna Associate professor krishnateja pharmacy college, tirupathi india
  • S Angala Parameswari Associate professor krishnateja pharmacy college, tirupathi india
  • B Haseena Banu Associate professor krishnateja pharmacy college, tirupathi india
  • P Jayachandra Reddy Principal krishnateja pharmacy college, tirupathi india

Keywords:

Sodium benzoate, Potassium sorbate, Food products, Spectrophotometer, School children, Dietary exposure, Acceptable daily intake, Total diet study

Abstract

Objective: According to Food Safety and Standards Authority of India (FSSAI) the preservatives, sodium benzoate and potassium sorbate belong to permitted class II preservatives. The aim of this study is to determine the concentration levels of these preservatives in food products that are consumed by school children and to assess the chronic dietary exposure by conducting the Total Diet Study (TDS).

Methods: The quantitative determination was carried out by UV spectrophotometer. The absorbance for sodium benzoate and potassium sorbate were measured at 228 and 250 nm respectively. The 24-hour diet recall method was used to estimate the amount of food ate in last 24 hours. For estimation of preservative exposure dietary modelling techniques were utilized which combine the amount of preservative concentration present in that food with the amount of food consumed. Then the dietary exposure was assessed by considering the Acceptable Daily Intake (ADI).

Results: The results include chemical concentration levels of the foods analyzed as well as estimated dietary exposures and contributions to the exposure from different foods. The obtained mean concentration of sodium benzoate was found to be425 ppm for sauces, 161 ppm for pickles and 80 ppm for soft drinks. Potassium sorbate was found to be 130 ppm for fruit juices,302 ppm for jellies and 380 ppm for jams. The highest mean dietary exposure for both the preservatives was observed in children of 2-7 years age group, the percentage exposure of sodium benzoate was 33% of the ADI and potassium sorbate was 17 % of the ADI.

Conclusion: This study can enlighten the public on the consumption of preservative containing food products within the limit and encourages to eating fresh preservative free foods.


 

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References

Saranraj P, Geetha M. Microbial spoilage of bakery products and its control by preservatives. Int J Pharm Biol Arch 2012;3:38-48.

Erich L, Martin J, Nico Raczek. Sorbic acid in Ullmann’s Encyclopedia of Industrial Chemistry. Weinheim, Germany: Wiley-VCH Publishers; 2000.

Heydaryinia A, Veissi M, Sadadi A. A Comparative study of the effects of the two preservatives, sodium benzoate and potassium sorbate on Aspergillus niger and Pencillium notatum. Jundishapur J Microbiol 2011;4:301-7.

Sofos JN, Busta F. Antimicrobial activity of sorbate. J Food Prot 1991;44:614-21.

Yogesh Pounikar, Pushpendra Jain, Navneet Khurana, L Omray, S Patil, Asmita Gajbhiye. Formulation and characterization of Aloevera cosmetic herbal hydrogel. Int J Pharm Pharm Sci 2012;4:85-6.

Guynot ME, Ramos AJ, Sanchis V, Marin S. Study of benzoate, propionate, and sorbate salts as mould spoilage inhibitors on intermediate moisture bakery products of low pH (4.5-5.5). Int J Food Microbiol 2005;101:161-8.

Saad B, Bari MF, Saleh MI, Ahmad K, Talib MK. Simultaneous determination of preservatives (benzoic acid, sorbic acid, methylparaben and propylparaben) in food stuffs using high-performance liquid chromatography. J Chromatogr A 2005;1073:393-7.

Isabel MF, Eual IM, Paula B, Margarida AF. Simultaneous determination of benzoic and sorbic acids in quince jam by HPLC. Food Res Int 2001;33:113-7.

T founi SAV, Toledo MCF. Determination of benzoic acid and sorbic acids in Brazilian food. Food Control 2002;13:125-9.

Kuo KL, Hsieh YZ. Determination of preservatives in food products by cyclodextrin-modified capillary electrophoresis with multi wavelength detection. J Chromatogr A 1997;768:334-41.

Hsui Jung, Youk Meng Choong. A simple method for the simultaneous determination of various preservatives in liquid foods. J Food Drug Anal 1999;7:291-304.

World Health Organization. Evaluation of certain food additives forty sixth report of the joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series Geneva: WHO Press; 1997. p. 868.

World Health Organization. Evaluation of certain food additives seventeenth report of the joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series Geneva: WHO Press; 1974. p. 539.

Bronaugh RL, Stewart RF, Congdon ER. Methods for in vitro percutaneous absorption studies II Animal methods for human skin. Toxicol Appl Pharm 1982;62:481-8.

Coverly J, Peters L, Whittle E, Basketter DA. Susceptibility to skin stinging, non-immunologic contact urticarial and acute skin irritation. Contact Dermatitis 1998;38:90-5.

Lahti A, Maibach HI. An animal model for non-immunologic contact uriticaria. Toxicol Appl Pharmacol 1984;76:219-24.

Freedman BJ. Asthma induced by Sulphur dioxide, benzoate and tartrazine contained in orange drinks. Clin Allergy 1977;7:407-15.

Tulamait A, Laghi F, Mikrut K, Carey RB. Potassium sorbate reduces gastric colonization in patients receiving mechanical ventilization. J Crit Care 2005;20:281-7.

Mamur S, Yuzbasioglu D, unal F, Yilmaz S. Does potassium sorbate induce genotoxic or mutagenic effects in lymphocytes? Toxicol In Vitro 2010;24:790-4.

Kitano K, Fukukawa T, Ohtsuji Y, Masuda T, Yamaguchi H. Mutagenicity and DNA–damaging activity caused by decomposed products of potassium sorbate reacting with ascorbic acid in the presence of Fe salt. Food Chem Toxicol 2002;40:1589-94.

Hendy RJ, Hardy J, Gaunt IF, Kiss IS, Butterworth KR. Long term toxicity studies of sorbic acid in mice. Food Cosmet Toxicol 1976;14:381-6.

Gaunt IF, Butterworth KR, Hardy J, Gangolli SD. Long term toxicity of sorbic acid in rat. Food Cosmet Toxicol 1975;13:31-45.

Horwitz W. AOAC Official method 960.38 benzoic acid in non-solid food and beverages. 17thed. Gaithersburg, Md: AOAC Int; 2000.

International Organization for Standardization. Fruits, vegetables and derived products--Determination of sorbic acid content ISO 5519:2008. Geneva, Switzerland: ISO; 2008.

Food Standards Australia and New Zealand (FSANZ). Principles and practices of dietary exposure assessment for food regulatory purposes. Canberra: FSANZ. Available from: http://www.foodstandards.gov.au/science/exposure/documents/Principles%20_%20practices%20exposure%20assessment%202009. pdf. [Cited 2009 Aug 15].

Food Safety and Standards Authority of India (FSSAI). Food safety and standards (food products standards and food additives) regulations. New Delhi: Int Law Book Company; 2011. p. 449-97.

Vandevijvere S, Andjelkovic M, De Wil M, Vinkx C, Huybrechts I, Van Loco J, et al. Estimate of intake of benzoic acid in the Belgian adult population. Food Addit Contam Part A 2009;26:958-68.

Mostafa Delavar, Rita Ahmadi Araghi, Amir Mohammad Kazemifar, Mahdi Abdollahi, Behnoush Ansari. Determination of benzoate level in canned pickles and pickled cucumbers in food producing factories in markazi province and those that their products were sold in Arak City, Iran. Iranian J Toxicol 2012;6:686-90.

Food Standards Australia and New Zealand (FSANZ). Benzoates, sul¬phites and sorbates inthe food supply. Canberra: FSANZ. Available from: http://www.foodstandards.gov.au/ scienceandeducation/factsheets/factsheets2005/benzoatessulphitesan2965. cfm. [Cited 2010 Dec 5].

Konstansa Lazarević, DuÅ¡ica Stojanović, NataÅ¡a RanÄić. Estimated daily intake of benzoic acid through food additives in adult population of south east Serbia. Cent Eur J Public Health 2011;19:228–31.

Yoon HJ, Cho YH, Park J, Lee CH, Park SK, Cho YJ, et al. Assessment of estimated daily intakes of benzoates for average and high consumers in Korea. Food Addit Contam 2003;20:127-35.

Leth T, Christensen T, Larsen IK. Estimated intake of benzoic and sorbic acids in Denmark. Food Addit Contam Part A 2010;27:783-92.

Ishiwata H, Yamada T, Yoshiike N, Nishijima M, Kawamoto A, Uyama Y. Daily intake of food additives in Japan in five age groups estimated by the market basket method. Eur Food Res Technol 2002;215:367–74.

Published

01-07-2015

How to Cite

Reddy, M. V., G. Aruna, S. A. Parameswari, B. H. Banu, and P. J. Reddy. “ESTIMATED DAILY INTAKE AND EXPOSURE OF SODIUM BENZOATE AND POTASSIUM SORBATE THROUGH FOOD PRODUCTS IN SCHOOL CHILDREN OF TIRUPATI, INDIA”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, no. 7, July 2015, pp. 129-33, https://journals.innovareacademics.in/index.php/ijpps/article/view/6114.

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Original Article(s)