RHEUMATOID ARTHRITIS: MOLECULAR BASIS AND CURES FROM NATURE

Authors

  • Subhashis Paul Department of Zoology, University of North Bengal
  • Abhaya Prasad Das Department of Botany, University of North Bengal
  • Soumen Bhattacharjee Cell and Molecular Biology Laboratory, Department of Zoology, University of North Bengal, P. O. North Bengal University, Raja Rammohunpur, Siliguri, District-Darjeeling, West Bengal, 734 013, India

Keywords:

Rheumatoid arthritis, Medicinal plant

Abstract

Incidences of arthritic diseases in human have seen recent increases which are thought to have resulted from a complex interplay of several factors, such as changes in lifestyle, nutritional insufficiencies, aging and genetic factors. These putative factors possibly lead to different arthritic diseases in humans affecting 2-5% of the total population in India. This group of diseases results in serious malfunction and structural abnormalities in the patient body leading to permanent and substantial immovability of joints. Conventional medicinal systems usually elicit various side effects in which the defence mechanism of the body i.e. the immune system is compromised. In the last few decades many alternative medicinal systems have been developed that show promising effects on treating such diseases. Many purified compounds from natural origin, both from plants and animal sources have shown promise and many new compounds are continuingly being identified which have no marked side effects. In the light of modern science and technology, different natural products and ethnic practices that ensure health, seem to be the best weapon to combat these diseases. Endemic as well as naturalized plants from India have been screened by several groups for their anti-arthritic activities. The review summarizes our current knowledge on the molecular basis of Rheumatoid Arthritis and discusses the efficacious roles of those natural products, especially of plant origin, in arthritic conditions.

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Author Biographies

Subhashis Paul, Department of Zoology, University of North Bengal

Research Scholar

Abhaya Prasad Das, Department of Botany, University of North Bengal

Full Professor

Soumen Bhattacharjee, Cell and Molecular Biology Laboratory, Department of Zoology, University of North Bengal, P. O. North Bengal University, Raja Rammohunpur, Siliguri, District-Darjeeling, West Bengal, 734 013, India

Assistant Professor of Zoology

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Published

01-07-2015

How to Cite

Paul, S., A. P. Das, and S. Bhattacharjee. “RHEUMATOID ARTHRITIS: MOLECULAR BASIS AND CURES FROM NATURE”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, no. 7, July 2015, pp. 30-39, https://www.innovareacademics.in/journals/index.php/ijpps/article/view/6407.

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