TY - JOUR AU - Patwari, Bhargab Nath AU - Ahmed, Abdul Baqee AU - Das, Trishna AU - Sengupta, Rupa PY - 2014/07/01 Y2 - 2024/03/29 TI - PHYTOCHEMICAL SCREENING AND ANALGESIC EFFECTS OF ETHANOLIC EXTRACT OF PLANT MURDANIA NUDIFLORA (L) BRENAN (COMMELINACEAE) IN ALBINO MICE USING HOT PLATE METHOD JF - International Journal of Pharmacy and Pharmaceutical Sciences JA - Int J Pharm Pharm Sci VL - 6 IS - 7 SE - Original Article(s) DO - UR - https://journals.innovareacademics.in/index.php/ijpps/article/view/1751 SP - 512-515 AB - <p><strong>Objective: </strong><em>Murdania nudiflora (L) Brenan</em> (Commelinaceae) has long been used in folk medicine in treatment of many diseases. In this study, attempts have been made for pharmacological screening of the plant <em>Murdania nudiflora (L) Brenan</em> (Commelinaceae) for analgesic activity and presence of different phytochemicals.</p><p><strong>Methods: </strong>To this end, ethanolic extract of <em>Murdania nudiflora (L) Brenan</em> (Commelinaceae) was evaluated for analgesic properties using plate reaction time in mice and phytochemical screening of the plant was done by different methods.</p><p><strong>Results: </strong>The analgesic study showed that the ethanolic extract of the leaves have significant analgesic effects (P &lt; 0.05; P &lt; 0.001) as compared to morphine sulphate (10 mg/kg) used as a standard drug. The result of the preliminary phytochemical studies revealed the presence of tannins, flavonoids, saponins, alkaloids as a whole and which are reported to be responsible for the analgesic and anti-inflammatory activities in many medicinal plants of this family.</p><p><strong>Conclusion: </strong>From these studies, it may be concluded that ethanol extracts of <em>Murdania nudiflora</em> (L) Brenan may contain novel bioactive principles with analgesic activity. Further study is required for evaluation of active principle(s) in different animal models.</p> ER -