SYNTHESIS AND INVISTIGATION OF NEW CYCLICMANNICH BASES

Authors

  • NAGHAM MAHMOOD ALJAMALI

Abstract

The aim of this paper , cyclic compounds of  mannich bases were synthesized through condensation of diketone compounds with ammonia or amine derivatives to give enamino  ketone as intermediate , which reacts with aldehyde compounds to yield compounds [1-4] .

All structures of formated compounds were characterized by (C.H.N)elementary analysis , 1HNMRspectra and FT-IRspectra.The data obtained gave good support for synthesized compounds [1-4] .

 

Keyword :CyclicMannich Bases ,intermediate.

References

–Wagner .E, Becan.L and Nowakowska. E.,(2004),Bioory . Med.Chem.,12, 265.

–Kidwai . M , Venkatraman . R , Gary . R and Bhushan .K ., (2000) , J . chem. Res ., 5 , 586.

– Kalluraya . B , lingappa .B and Rai . N ., (2007) , Phosphorous , sulphur and silicon and related elements ., 182 , 1393.

– Sridhar . S , Pandeya . S , Stables . J and Ramesh . A ., (2002), Eur . J . Pharm . Science ., 16 , 129.

– Lingappa .B , Girisha .K , Balakrishna . K , Satheesh . R and Nalilu . S ., (2008) , 1 , 47B , 1858–1864.

– Anil . S , Sanjay . K and Jagir . S, (2008) ., 1 , 67 , 95 – 111.

– Dilmaghani . K , Zeynizadeh . B and Mirzaei . M ., Shiraz , 10 , 11 (2005) .

– Xia . J and Wang . G ., (2005) , Synthesis ., 2379 – 2383.

– Lee . K and Ko . K .,Bull ., (2002) , Korean . Chem. Soc ., 23 , 1505 – 1506.

– Lee . J and ko . K ,Bull . (2004) ,Korean . Chem. Soc ., 25 ,19 – 20.

– Arguello . J , Nunez . V , Sturm . J and Suuella . (2004) ,J ., Electrochim . Acta ., 49 , 4849 – 4856.

-Heravi .M and Ghassemzadeh .M., (2005).,Phosphorus. Sulfur& Silicon.,180,347-351

-Heravi,M., Dirkwand.F, Oskooie.H and Ghassemzadeh.M., (2005)., Heterocycle .Common ,11,75-78

-Heravi.M, Dirikvand .F ,Hassanpour .S,Bakhtiari .K , Baamoharram .F and Oskooie .H., (2007)., Bioorg.Med. Chem. Lett.,17,1008 -1012

-Chai. L, Zhao.Y ,Sheng.D& Liu .Z., (2006).,Tetrahedron .Lett .,47,9283-9285

– Manuela.M ,Cidalia.M., Tetrahedron, 67,5189-5198, (2011)., Cited by IVSL of Iraq.

– Maria.G, and Tomas.T., Eur.J.Org.Chem ,849-861 (2006)., Cited by IVSL of Iraq.

–Nagham .M.Aljamali ., (2013) ,Pharma.INN.J .,1,11,73-79.

-Nagham .Aljamali . ,(2012).,Pharma.INN.J., 1,12,64-71

Published

01-07-2013

How to Cite

, N. M. A. (2013). SYNTHESIS AND INVISTIGATION OF NEW CYCLICMANNICH BASES. Innovare Journal of Sciences, 1(2), 8–12. Retrieved from https://journals.innovareacademics.in/index.php/ijs/article/view/231